Go to Graph

proteins with alternating alpha-helices and beta-strands

Derived from SCOP 51349

## Class

class Alpha and beta proteins (a/b) (1000002)proteins with alternating alpha-helices and beta-strands

Derived from SCOP 51349

## Children

- fold Canonical Rossmann fold (2000005)

3 layers, alpha/beta/alpha, parallel beta-sheet of 6 strands, order 321456

Derived from SCOP 51734 - fold OCD-type extended Rossmann fold (2000149)

3 layer alpha/beta/alpha, parallel beta-sheet of 8 strands, order 32145867 - fold Rossmann(2x2)oid (2000009)

3 layers: a/b/a, parallel beta-sheet of 4 strands, 2134

Derived from SCOP 53222 - fold TPM/PMT domain-like (2000015)

3 layers, a/b/a; parallel sheet of 5 strands, order 51423

Derived from SCOP 159501 - fold Rossmann(2x3)oid (Flavodoxin-like) (2000016)

3 layers, a/b/a, parallel beta-sheet of 5 strand, order 21345

Derived from SCOP 52171 - fold FAD/NAD(P)-binding domain (2000021)

core: 3 layers, b/b/a, central parallel beta-sheet of 5 strands, order 32145, top antiparallel beta-sheet of 3 strands, meander

Derived from SCOP 51904 - fold Formyltransferase-type (2000023)

3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3214567, strand 6 is antiparallel to the rest

Derived from SCOP 53327 - fold Thioredoxin fold (2000024)

core: 3 layers, a/b/a, mixed beta-sheet of 4 strands, order: 2134, strand 3 is antiparallel to the rest

Derived from SCOP 52832 - fold Rossmann(3x2)oid (2000025)

core: 3 layers, a/b/a , parallel beta-sheet of 5 strands, order 32145

Derived from SCOP 52373 - fold ClpP-type beta-alpha superhelix (2000027)

core: 4 turns of (beta-beta-alpha)n right-handed superhelix, capped at C-end by an antiparallel beta-strand

Derived from SCOP 52095 - fold TIM beta/alpha-barrel (2000031)

(beta-alpha)8; parallel beta-sheet barrel, closed, n=8, S=8, strand order 12345678 (anticlockwise); the first seven superfamilies have similar phosphate-binding sites

Derived from SCOP 51350 - fold FAD/NAD(P)-binding domain, circularly permuted variant 1 (2000034)

core: 3 layers, b/b/a, central parallel beta-sheet of 5 strands, order 15234, top antiparallel beta-sheet of 3 strands, meander

Derived from SCOP 51904 - fold P-loop containing nucleoside triphosphate hydrolases (2000039)

3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

Derived from SCOP 52539 - fold PRTase-like (2000040)

3 layers, a/b/a, mixed beta-sheet of 6 strands, order 321456, strand 3 is antiparallel to the rest

Derived from SCOP 53270 - fold Resolvase-like (2000045)

Core: 3 layers: a/b/a, mixed beta-sheet of 5 strands, order 21345, strand 5 is antiparallel to the rest

Derived from SCOP 53040 - fold NDP Glycotransferase-like (2000056)

3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3214657, strand 6 is antiparallel to the rest

Derived from SCOP 53447 - fold FPGS-type ribokinase-like fold (2000058)

core: 3 layers: a/b/a, mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest

Derived from SCOP 53612 - fold SBP2HA-like (2000060)

hypothetical single-domain ancestral fold of type 2 solute binding proteins;

3 layers, a/b/a; mixed beta-sheet of 5 strands, order 21354, strand 5 is antiparallel to the rest

Derived from SCOP 53849 - fold Ribonuclease H-like motif (2000067)

2 layers: a/b, mixed beta-sheet of 5 strands, order 32145, strand 2 is antiparallel to the rest; usually followed by one or more helices forming a third layer on the other side of the beta-sheet or swapping between different domains

Derived from SCOP 53066 - fold alpha/beta-Hydrolases (2000076)

core: 3 layers, a/b/a, mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

Derived from SCOP 53473 - fold Restriction endonuclease-like (2000077)

alpha-beta(3)-alpha-beta; 3 layers, a/b/a, mixed beta-sheet, order: 1234, strands 2 is antiparallel to the rest

Derived from SCOP 52979 - fold FPGS C-terminal domain-like (2000079)

3 layers: a/b/a, mixed beta-sheet of 6 strands, order 126345, strand 1 is antiparallel to the rest

Derived from SCOP 53243 - fold MoeB-like (2000082)

3 layers: a/b/a, mixed beta-sheet of 8 strands, order 32145678, strands 6 and 8 are antiparallel to the rest

Derived from SCOP 69571 - fold Methyltransferase-like (2000088)

core: 3 layers, a/b/a, mixed beta-sheet of 7 strands, order 3214576, strand 7 is antiparallel to the rest

Derived from SCOP 53334 - fold Thiolase-like (2000091)

consists of two similar subdomains related by pseudo dyad; 5 layers: a/b/a/b/a, two similar mixed beta-sheet of 5 strands each, order: 32451, strand 5 is antiparallel to the rest

Derived from SCOP 53900 - fold Tetrapyrrole methylase C-terminal lobe-like (2000107)

3 layers, a/b/a; mixed sheet of 5 strands, order 12534, strands 4 & 5 are antiparallel to the rest

Derived from SCOP 53789 - fold GltS central domain-like (2000115)

3 layers, a/b/a; parallel beta-sheet, order 15432; probable rudiment form of a beta/alpha(8) barrel, resulted from the deletion of the most of the N-terminal half - fold MurF/HprK domain-like (2000128)

3 layers, a/b/a; mixed beta-sheet of 5 strands, order 15432, strand 1 is antiparallel to the rest; partial similarity to the swivelling domain fold

Derived from SCOP 63417 - fold SDR-type extended Rossmann fold (2000148)

3 layer alpha/beta/alpha, parallel beta-sheet of 7 strands, order 3214567, left-handed crossover connection between strands 6 and 7 - fold CoA-binding domain-type Rossmann fold (2000152)

3 layer alpha/beta/alpha, mixed, mostly parallel beta-sheet of 7 strands, order 3421567, strand 3 is antiparallel to the rest - fold Variant Rossmann(2x2)oid (2000153)

not a true fold: different evolutionary elaborations of Rossmann(2x2)oid

Derived from SCOP 53222 - fold 6PGDH-type extended Rossmann fold (2000154)

3 layer alpha/beta/alpha, mixed beta-sheet of 8 strands, order 32145678, strands 7 and 8 are parallel to each other and antiparallel to the rest - fold DAO-type FAD/NAD(P)-binding domain (2000155)

variant of FAD/NAD(P)-binding domain, in which an alpha-helix replaces the top meander beta-sheet: 3 layers, a/b/a, parallel beta-sheet of 5 strands, order 32145

Derived from SCOP 51904 - fold YrdC/RibB-like (2000159)

core: alpha-beta(2)-alpha-beta-alpha(2)-beta(2)-alpha-beta-alpha-beta; 3 layers, a/b/a; mixed twisted sheet of 7 strands, order: 7126354; strands 7 and 1 are parallel to each other

Derived from SCOP 55820 - fold SBP2HA-like circular permuted variant 1 (2000161)

3 layers, a/b/a; mixed beta-sheet of 5 strands, order 51423, strand 1 is antiparallel to the rest

Derived from SCOP 53849 - fold Sua5 domain-like (2000162)

3 layers, a/b/a; parallel beta-sheet of 5 strands, order 51423 - fold Anticodon-binding domain-like (2000335)

3 layers: a/b/a, mixed beta-sheet of five strands, order 21345, strand 4 is antiparallel to the rest

Derived from SCOP 52953 - fold Phosphoglycerate mutase-like (2000503)

core: 3 layers, a/b/a, mixed beta-sheet of 6 strands, order 324156, strand 5 is antiparallel to the rest

Derived from SCOP 53253 - fold PEPCK/HprK-like alpha/beta barrel (2001024)

3 layers, a/b/b; mixed beta-sheet of 7 strands, order: 4312576, strands 1, 4 and 6 are antiparallel to the rest; the first five strands form a barrel-like structure with 2 helices packed on one side

Derived from SCOP 53794 - fold PEPCK N-terminal domain-like (2001096)

mixed beta-sheet of 8 strands, order: 14568723; topology is partly similar to that of the PEPCK C-terminal domain

Derived from SCOP 68922 - fold HAD-like (2001153)

3 layers: a/b/a, parallel beta-sheet of 6 strands, order 321456

Derived from SCOP 56783 - fold Rossmann(3x4)oid (2001244)

C-terminally extended Rossmann-fold: 3 layers, a/b/a , parallel beta-sheet of 7 strands, order 3214567

Derived from SCOP 52373 - fold Simibi-like (2001245)

3 layers: a/b/a, parallel beta-sheet of seven strands; order 3241567

Derived from SCOP 52539 - fold TsaE-like (2001246)

3 layers: a/b/a; mixed beta-sheet of 7 strands, order 3452671), strands 3 and 7 are antiparallel to the rest

Derived from SCOP 52539 - fold THEP1-like (2001247)

3 layers: a/b/a, mixed beta-sheet of 7 strands, order: 7165234, strand 3 is antiparallel to the rest; variant of RecA-like fold

Derived from SCOP 52539 - fold RecA-like basic (2001248)

3 layers: a/b/a, parallel beta-sheet of 6 strands, order:615423

Derived from SCOP 52539 - fold RecA-like classic (2001249)

3 layers: a/b/a, mixed, mostly parallel beta-sheet of 8 strands, order: 87615423, strand 7 is antiparallel to the rest

Derived from SCOP 52539 - fold ABC domain-like (2001251)

4 layers: a/b/a/b, the inner mixed beta-sheet of six strands, order 651432, strand 6 is antiparallel to the rest

Derived from SCOP 52539 - fold C-teminally truncated RecA-like (2001259)

3 layers: a/b/a, parallel beta-sheet of 5 strands, order:15423

Derived from SCOP 52539 - fold G domain-like (2001260)

3 layers: a/b/a, mixed, predominantly parallel beta-sheet, order: 231456, strand 2 is antiparallel to the rest

Derived from SCOP 52539 - fold Circularly permuted G domain-like (2001261)

3 layers: a/b/a, mixed, predominantly parallel beta-sheet, order: 321465, strand 6 is antiparallel to the rest; P-loop is after strand 4

Derived from SCOP 52539