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Class

class Alpha and beta proteins (a/b) (1000002)
proteins with alternating alpha-helices and beta-strands
Derived from SCOP 51349

Children

  • fold Canonical Rossmann fold (2000005)
    3 layers, alpha/beta/alpha, parallel beta-sheet of 6 strands, order 321456
    Derived from SCOP 51734
  • fold OCD-type extended Rossmann fold (2000149)
    3 layer alpha/beta/alpha, parallel beta-sheet of 8 strands, order 32145867
  • fold Rossmann(2x2)oid (2000009)
    3 layers: a/b/a, parallel beta-sheet of 4 strands, 2134
    Derived from SCOP 53222
  • fold TPM/PMT domain-like (2000015)
    3 layers, a/b/a; parallel sheet of 5 strands, order 51423
    Derived from SCOP 159501
  • fold Rossmann(2x3)oid (Flavodoxin-like) (2000016)
    3 layers, a/b/a, parallel beta-sheet of 5 strand, order 21345
    Derived from SCOP 52171
  • fold FAD/NAD(P)-binding domain (2000021)
    core: 3 layers, b/b/a, central parallel beta-sheet of 5 strands, order 32145, top antiparallel beta-sheet of 3 strands, meander
    Derived from SCOP 51904
  • fold Formyltransferase-type (2000023)
    3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3214567, strand 6 is antiparallel to the rest
    Derived from SCOP 53327
  • fold Thioredoxin fold (2000024)
    core: 3 layers, a/b/a, mixed beta-sheet of 4 strands, order: 2134, strand 3 is antiparallel to the rest
    Derived from SCOP 52832
  • fold Rossmann(3x2)oid (2000025)
    core: 3 layers, a/b/a , parallel beta-sheet of 5 strands, order 32145
    Derived from SCOP 52373
  • fold ClpP-type beta-alpha superhelix (2000027)
    core: 4 turns of (beta-beta-alpha)n right-handed superhelix, capped at C-end by an antiparallel beta-strand
    Derived from SCOP 52095
  • fold TIM beta/alpha-barrel (2000031)
    (beta-alpha)8; parallel beta-sheet barrel, closed, n=8, S=8, strand order 12345678 (anticlockwise); the first seven superfamilies have similar phosphate-binding sites
    Derived from SCOP 51350
  • fold FAD/NAD(P)-binding domain, circularly permuted variant 1 (2000034)
    core: 3 layers, b/b/a, central parallel beta-sheet of 5 strands, order 15234, top antiparallel beta-sheet of 3 strands, meander
    Derived from SCOP 51904
  • fold P-loop containing nucleoside triphosphate hydrolases (2000039)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
    Derived from SCOP 52539
  • fold PRTase-like (2000040)
    3 layers, a/b/a, mixed beta-sheet of 6 strands, order 321456, strand 3 is antiparallel to the rest
    Derived from SCOP 53270
  • fold Resolvase-like (2000045)
    Core: 3 layers: a/b/a, mixed beta-sheet of 5 strands, order 21345, strand 5 is antiparallel to the rest
    Derived from SCOP 53040
  • fold NDP Glycotransferase-like (2000056)
    3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3214657, strand 6 is antiparallel to the rest
    Derived from SCOP 53447
  • fold FPGS-type ribokinase-like fold (2000058)
    core: 3 layers: a/b/a, mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
    Derived from SCOP 53612
  • fold SBP2HA-like (2000060)
    hypothetical single-domain ancestral fold of type 2 solute binding proteins;
    3 layers, a/b/a; mixed beta-sheet of 5 strands, order 21354, strand 5 is antiparallel to the rest
    Derived from SCOP 53849
  • fold Ribonuclease H-like motif (2000067)
    2 layers: a/b, mixed beta-sheet of 5 strands, order 32145, strand 2 is antiparallel to the rest; usually followed by one or more helices forming a third layer on the other side of the beta-sheet or swapping between different domains
    Derived from SCOP 53066
  • fold alpha/beta-Hydrolases (2000076)
    core: 3 layers, a/b/a, mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest
    Derived from SCOP 53473
  • fold Restriction endonuclease-like (2000077)
    alpha-beta(3)-alpha-beta; 3 layers, a/b/a, mixed beta-sheet, order: 1234, strands 2 is antiparallel to the rest
    Derived from SCOP 52979
  • fold FPGS C-terminal domain-like (2000079)
    3 layers: a/b/a, mixed beta-sheet of 6 strands, order 126345, strand 1 is antiparallel to the rest
    Derived from SCOP 53243
  • fold MoeB-like (2000082)
    3 layers: a/b/a, mixed beta-sheet of 8 strands, order 32145678, strands 6 and 8 are antiparallel to the rest
    Derived from SCOP 69571
  • fold Methyltransferase-like (2000088)
    core: 3 layers, a/b/a, mixed beta-sheet of 7 strands, order 3214576, strand 7 is antiparallel to the rest
    Derived from SCOP 53334
  • fold Thiolase-like (2000091)
    consists of two similar subdomains related by pseudo dyad; 5 layers: a/b/a/b/a, two similar mixed beta-sheet of 5 strands each, order: 32451, strand 5 is antiparallel to the rest
    Derived from SCOP 53900
  • fold Tetrapyrrole methylase C-terminal lobe-like (2000107)
    3 layers, a/b/a; mixed sheet of 5 strands, order 12534, strands 4 & 5 are antiparallel to the rest
    Derived from SCOP 53789
  • fold GltS central domain-like (2000115)
    3 layers, a/b/a; parallel beta-sheet, order 15432; probable rudiment form of a beta/alpha(8) barrel, resulted from the deletion of the most of the N-terminal half
  • fold MurF/HprK domain-like (2000128)
    3 layers, a/b/a; mixed beta-sheet of 5 strands, order 15432, strand 1 is antiparallel to the rest; partial similarity to the swivelling domain fold
    Derived from SCOP 63417
  • fold SDR-type extended Rossmann fold (2000148)
    3 layer alpha/beta/alpha, parallel beta-sheet of 7 strands, order 3214567, left-handed crossover connection between strands 6 and 7
  • fold CoA-binding domain-type Rossmann fold (2000152)
    3 layer alpha/beta/alpha, mixed, mostly parallel beta-sheet of 7 strands, order 3421567, strand 3 is antiparallel to the rest
  • fold Variant Rossmann(2x2)oid (2000153)
    not a true fold: different evolutionary elaborations of Rossmann(2x2)oid
    Derived from SCOP 53222
  • fold 6PGDH-type extended Rossmann fold (2000154)
    3 layer alpha/beta/alpha, mixed beta-sheet of 8 strands, order 32145678, strands 7 and 8 are parallel to each other and antiparallel to the rest
  • fold DAO-type FAD/NAD(P)-binding domain (2000155)
    variant of FAD/NAD(P)-binding domain, in which an alpha-helix replaces the top meander beta-sheet: 3 layers, a/b/a, parallel beta-sheet of 5 strands, order 32145
    Derived from SCOP 51904
  • fold YrdC/RibB-like (2000159)
    core: alpha-beta(2)-alpha-beta-alpha(2)-beta(2)-alpha-beta-alpha-beta; 3 layers, a/b/a; mixed twisted sheet of 7 strands, order: 7126354; strands 7 and 1 are parallel to each other
    Derived from SCOP 55820
  • fold SBP2HA-like circular permuted variant 1 (2000161)
    3 layers, a/b/a; mixed beta-sheet of 5 strands, order 51423, strand 1 is antiparallel to the rest
    Derived from SCOP 53849
  • fold Sua5 domain-like (2000162)
    3 layers, a/b/a; parallel beta-sheet of 5 strands, order 51423
  • fold Anticodon-binding domain-like (2000335)
    3 layers: a/b/a, mixed beta-sheet of five strands, order 21345, strand 4 is antiparallel to the rest
    Derived from SCOP 52953
  • fold Phosphoglycerate mutase-like (2000503)
    core: 3 layers, a/b/a, mixed beta-sheet of 6 strands, order 324156, strand 5 is antiparallel to the rest
    Derived from SCOP 53253
  • fold PEPCK/HprK-like alpha/beta barrel (2001024)
    3 layers, a/b/b; mixed beta-sheet of 7 strands, order: 4312576, strands 1, 4 and 6 are antiparallel to the rest; the first five strands form a barrel-like structure with 2 helices packed on one side
    Derived from SCOP 53794
  • fold PEPCK N-terminal domain-like (2001096)
    mixed beta-sheet of 8 strands, order: 14568723; topology is partly similar to that of the PEPCK C-terminal domain
    Derived from SCOP 68922
  • fold HAD-like (2001153)
    3 layers: a/b/a, parallel beta-sheet of 6 strands, order 321456
    Derived from SCOP 56783
  • fold Rossmann(3x4)oid (2001244)
    C-terminally extended Rossmann-fold: 3 layers, a/b/a , parallel beta-sheet of 7 strands, order 3214567
    Derived from SCOP 52373
  • fold Simibi-like (2001245)
    3 layers: a/b/a, parallel beta-sheet of seven strands; order 3241567
    Derived from SCOP 52539
  • fold TsaE-like (2001246)
    3 layers: a/b/a; mixed beta-sheet of 7 strands, order 3452671), strands 3 and 7 are antiparallel to the rest
    Derived from SCOP 52539
  • fold THEP1-like (2001247)
    3 layers: a/b/a, mixed beta-sheet of 7 strands, order: 7165234, strand 3 is antiparallel to the rest; variant of RecA-like fold
    Derived from SCOP 52539
  • fold RecA-like basic (2001248)
    3 layers: a/b/a, parallel beta-sheet of 6 strands, order:615423
    Derived from SCOP 52539
  • fold RecA-like classic (2001249)
    3 layers: a/b/a, mixed, mostly parallel beta-sheet of 8 strands, order: 87615423, strand 7 is antiparallel to the rest
    Derived from SCOP 52539
  • fold ABC domain-like (2001251)
    4 layers: a/b/a/b, the inner mixed beta-sheet of six strands, order 651432, strand 6 is antiparallel to the rest
    Derived from SCOP 52539
  • fold C-teminally truncated RecA-like (2001259)
    3 layers: a/b/a, parallel beta-sheet of 5 strands, order:15423
    Derived from SCOP 52539
  • fold G domain-like (2001260)
    3 layers: a/b/a, mixed, predominantly parallel beta-sheet, order: 231456, strand 2 is antiparallel to the rest
    Derived from SCOP 52539
  • fold Circularly permuted G domain-like (2001261)
    3 layers: a/b/a, mixed, predominantly parallel beta-sheet, order: 321465, strand 6 is antiparallel to the rest; P-loop is after strand 4
    Derived from SCOP 52539