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fold TIM beta/alpha-barrel (2000031)
(beta-alpha)8; parallel beta-sheet barrel, closed, n=8, S=8, strand order 12345678 (anticlockwise); the first seven superfamilies have similar phosphate-binding sites
Derived from SCOP 51350

Protein Type

Globular proteinsFold into compact units. Soluble in aqueous solutions

Children

Domains PDB ID RegionMethodResolution
Representative CF domain (8001524)
Dihydropyrimidine dehydrogenase [NADP+] precursor (EC 13.1.2) (DPD) (DHPDHase) (Dihydrouracil dehydrogenase) (Dihydrothymine dehydrogenase)
complexed with fad, fmn, fs4

Sus scrofa (9823)

 Q28943 544-844

Derived from SCOP domain 28628
rasmol icon 1H7W A:544-844 X-RAY DIFFRACTION 1.90
Clustered domains rasmol icon 1GT8 A:544-844 X-RAY DIFFRACTION 3.3
rasmol icon 1GT8 B:544-844 X-RAY DIFFRACTION 3.3
rasmol icon 1GT8 C:544-844 X-RAY DIFFRACTION 3.3
rasmol icon 1GT8 D:544-844 X-RAY DIFFRACTION 3.3
rasmol icon 1GTE A:544-844 X-RAY DIFFRACTION 1.65
rasmol icon 1GTE B:544-844 X-RAY DIFFRACTION 1.65
rasmol icon 1GTE C:544-844 X-RAY DIFFRACTION 1.65
rasmol icon 1GTE D:544-844 X-RAY DIFFRACTION 1.65
rasmol icon 1GTH A:544-844 X-RAY DIFFRACTION 2.25
rasmol icon 1GTH B:544-844 X-RAY DIFFRACTION 2.25
rasmol icon 1GTH C:544-844 X-RAY DIFFRACTION 2.25
rasmol icon 1GTH D:544-844 X-RAY DIFFRACTION 2.25
rasmol icon 1H7W B:544-844 X-RAY DIFFRACTION 1.90
rasmol icon 1H7W C:544-844 X-RAY DIFFRACTION 1.90
rasmol icon 1H7W D:544-844 X-RAY DIFFRACTION 1.90
rasmol icon 1H7X A:544-844 X-RAY DIFFRACTION 2.01
rasmol icon 1H7X B:544-844 X-RAY DIFFRACTION 2.01
rasmol icon 1H7X C:544-844 X-RAY DIFFRACTION 2.01
rasmol icon 1H7X D:544-844 X-RAY DIFFRACTION 2.01
Representative CF domain (8003317)
Ferredoxin-dependent glutamate synthase 2
complexed with 2og, f3s, fmn

Synechocystis sp. PCC 6803 (1148)

 P55038 905-1226

Derived from SCOP domain 86936
rasmol icon 1OFD A:869-1190 X-RAY DIFFRACTION 2.00
Clustered domains rasmol icon 1LLW A:869-1190 X-RAY DIFFRACTION 2.70
rasmol icon 1LLZ A:869-1190 X-RAY DIFFRACTION 3.00
rasmol icon 1LM1 A:869-1190 X-RAY DIFFRACTION 2.80
rasmol icon 1OFD B:869-1190 X-RAY DIFFRACTION 2.00
rasmol icon 1OFE A:869-1190 X-RAY DIFFRACTION 2.45
rasmol icon 1OFE B:869-1190 X-RAY DIFFRACTION 2.45
Representative CF domain (8017533)
Cytochrome b2, mitochondrial
complexed with fmn, hem, mpd, po4, pyr

Saccharomyces cerevisiae (4932)

 P00175 271-547

Derived from SCOP domain 72277
rasmol icon 1KBI A:191-467 X-RAY DIFFRACTION 2.3
Clustered domains rasmol icon 1FCB A:191-467 X-RAY DIFFRACTION 2.4
rasmol icon 1FCB B:191-467 X-RAY DIFFRACTION 2.4
rasmol icon 1KBI B:191-467 X-RAY DIFFRACTION 2.3
rasmol icon 1KBJ A:191-467 Some residues were not observed X-RAY DIFFRACTION 2.5
rasmol icon 1KBJ B:191-467 Some residues were not observed X-RAY DIFFRACTION 2.5
rasmol icon 1LCO A:191-467 X-RAY DIFFRACTION 2.9
rasmol icon 1LCO B:191-467 X-RAY DIFFRACTION 2.9
rasmol icon 1LDC A:191-467 Some residues were not observed X-RAY DIFFRACTION 2.9
rasmol icon 1LDC B:191-467 X-RAY DIFFRACTION 2.9
rasmol icon 1LTD A:191-467 X-RAY DIFFRACTION 2.6
rasmol icon 1LTD B:191-467 X-RAY DIFFRACTION 2.6
rasmol icon 1QCW A:191-467 Some residues were not observed X-RAY DIFFRACTION 2.75
rasmol icon 1QCW B:191-467 Some residues were not observed X-RAY DIFFRACTION 2.75
rasmol icon 1SZE A:191-467 Some residues were not observed X-RAY DIFFRACTION 3.00
rasmol icon 1SZE B:191-467 Some residues were not observed X-RAY DIFFRACTION 3.00
rasmol icon 1SZF A:191-467 X-RAY DIFFRACTION 2.70
rasmol icon 1SZF B:191-467 Some residues were not observed X-RAY DIFFRACTION 2.70
rasmol icon 1SZG A:191-467 X-RAY DIFFRACTION 2.70
rasmol icon 1SZG B:191-467 X-RAY DIFFRACTION 2.70
rasmol icon 2OZ0 A:191-467 X-RAY DIFFRACTION 2.80
rasmol icon 2OZ0 B:191-467 X-RAY DIFFRACTION 2.80
Representative CF domain (8017571)
tRNA-dihydrouridine synthase
complexed with fmn, so4

Thermotoga maritima (2336)

 Q9WXV1 3-232

Derived from SCOP domain 100693
rasmol icon 1VHN A:5-234 X-RAY DIFFRACTION 1.59
Representative CF domain (8017578)
Trimethylamine dehydrogenase (EC 15.8.2) (TMADh).
complexed with adp, fmn, fs4

Methylophilus methylotrophus W3A1 (2327)

 P16099 25-339

Derived from SCOP domain 28612
rasmol icon 1DJN A:24-338 X-RAY DIFFRACTION 2.2
Clustered domains rasmol icon 1DJN B:24-338 X-RAY DIFFRACTION 2.2
rasmol icon 1DJQ A:24-338 X-RAY DIFFRACTION 2.2
rasmol icon 1DJQ B:24-338 X-RAY DIFFRACTION 2.2

Methylophilus methylotrophus (17)

rasmol icon 1O94 A:24-338 X-RAY DIFFRACTION 2.00

Methylophilus methylotrophus (17)

rasmol icon 1O94 B:24-338 X-RAY DIFFRACTION 2.00

Methylophilus methylotrophus (17)

rasmol icon 1O95 A:24-338 X-RAY DIFFRACTION 3.70

Methylophilus methylotrophus (17)

rasmol icon 1O95 B:24-338 X-RAY DIFFRACTION 3.70
rasmol icon 2TMD A:24-338 X-RAY DIFFRACTION 2.4
rasmol icon 2TMD B:24-338 X-RAY DIFFRACTION 2.4
Representative CF domain (8017587)
2,4-dienoyl-CoA reductase [NADPH] (EC 13.1.34) (2,4-dienoyl coenzyme A reductase)
complexed with cl, fad, fmn, fs4, mde, nap

Escherichia coli (562)

 P42593 19-327

Derived from SCOP domain 95076
rasmol icon 1PS9 A:18-326 X-RAY DIFFRACTION 2.2