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Fold

fold Ribonuclease H-like motif (2000067)
2 layers: a/b, mixed beta-sheet of 5 strands, order 32145, strand 2 is antiparallel to the rest; usually followed by one or more helices forming a third layer on the other side of the beta-sheet or swapping between different domains
Derived from SCOP 53066

Protein Type

Globular proteinsFold into compact units. Soluble in aqueous solutions

Children

  • family MutS-like (4004015)
    Multidomain family of conserved domain architecture; different Pfam families for different parts: PF01624, PF05188, PF05192, PF05190 and PF00488
  • superfamily Actin-like ATPase domain (3000092)
    duplication: comprises two ribonuclease H-like subdomains
    Derived from SCOP 53067
  • superfamily Ribonuclease H-like (3000143)
    comprises one domain of this fold
    Derived from SCOP 53098
Domains PDB ID RegionMethodResolution
Representative CF domain (8003335)
Transcriptional regulator, XylR-related
complexed with gol, k

Thermotoga maritima (2336)

 Q9X0V1 72-184

Derived from SCOP domain 136641
rasmol icon 2HOE A:72-184 X-RAY DIFFRACTION 2.460
Representative CF domain (8003336)
Transcriptional regulator, XylR-related
complexed with gol, k

Thermotoga maritima (2336)

 Q9X0V1 200-343

Derived from SCOP domain 136640
rasmol icon 2HOE A:200-343 X-RAY DIFFRACTION 2.460
Representative CF domain (8003609)
Transposase

Escherichia virus Mu (10677)

 P07636 264-450

Derived from SCOP domain 33676
rasmol icon 1BCO A:264-450 X-RAY DIFFRACTION 2.4
Clustered domains rasmol icon 1BCM A:264-450 X-RAY DIFFRACTION 2.8
rasmol icon 1BCM B:264-450 X-RAY DIFFRACTION 2.8
rasmol icon 4FCY A:264-450 X-RAY DIFFRACTION 3.706
rasmol icon 4FCY B:264-450 X-RAY DIFFRACTION 3.706
Representative CF domain (8003799)
Actin, cytoplasmic 1
complexed with atp, ca, oc4, so4

Bos taurus (9913)

 P60712 6-136

Derived from SCOP domain 148710
rasmol icon 2OAN C:6-136 X-RAY DIFFRACTION 2.606
Clustered domains rasmol icon 1HLU A:6-136 X-RAY DIFFRACTION 2.65
rasmol icon 2BTF A:6-136 X-RAY DIFFRACTION 2.55
rasmol icon 2OAN A:6-136 X-RAY DIFFRACTION 2.606
rasmol icon 2OAN B:6-136 X-RAY DIFFRACTION 2.606
rasmol icon 2OAN D:6-136 X-RAY DIFFRACTION 2.606
rasmol icon 3U4L A:6-136 X-RAY DIFFRACTION 2.40
rasmol icon 3UB5 A:6-136 X-RAY DIFFRACTION 2.20
Representative CF domain (8003800)
Actin, cytoplasmic 1
complexed with atp, ca, oc4, so4

Bos taurus (9913)

 P60712 148-332

Derived from SCOP domain 148711
rasmol icon 2OAN C:148-332 X-RAY DIFFRACTION 2.606
Clustered domains rasmol icon 1HLU A:148-332 X-RAY DIFFRACTION 2.65
rasmol icon 2BTF A:148-332 X-RAY DIFFRACTION 2.55
rasmol icon 2OAN A:148-332 X-RAY DIFFRACTION 2.606
rasmol icon 2OAN B:148-332 X-RAY DIFFRACTION 2.606
rasmol icon 2OAN D:148-332 X-RAY DIFFRACTION 2.606
rasmol icon 3U4L A:148-332 X-RAY DIFFRACTION 2.40
rasmol icon 3UB5 A:148-332 X-RAY DIFFRACTION 2.20
Representative CF domain (8004426)
Hydrogenase maturation factor

Caldanaerobacter subterraneus subsp. tengcongensis MB4 (273068)

 Q8RDB0 397-482

rasmol icon 3VTH A:397-482 X-RAY DIFFRACTION 2.00
Clustered domains rasmol icon 3VTH B:397-482 X-RAY DIFFRACTION 2.00
rasmol icon 3VTI A:397-482 X-RAY DIFFRACTION 2.56
rasmol icon 3VTI B:397-482 X-RAY DIFFRACTION 2.56
Representative CF domain (8004427)
Hydrogenase maturation factor

Caldanaerobacter subterraneus subsp. tengcongensis MB4 (273068)

 Q8RDB0 498-727

rasmol icon 3VTH A:498-727 X-RAY DIFFRACTION 2.00
Clustered domains rasmol icon 3VTH B:498-727 X-RAY DIFFRACTION 2.00
rasmol icon 3VTI A:498-727 X-RAY DIFFRACTION 2.56
rasmol icon 3VTI B:498-727 X-RAY DIFFRACTION 2.56
Representative CF domain (8004441)
Putative 6-carbamoyltransferase, TobZPutative carbamoyltransferase

Streptoalloteichus tenebrarius (1933)

 Q70IY1 1-112

rasmol icon 3VEN A:1-112 X-RAY DIFFRACTION 1.570
Clustered domains rasmol icon 3VEO A:1-112 X-RAY DIFFRACTION 2.1870
rasmol icon 3VER A:1-112 X-RAY DIFFRACTION 2.340
rasmol icon 3VES A:1-112 X-RAY DIFFRACTION 2.230
rasmol icon 3VET A:1-112 X-RAY DIFFRACTION 2.200
rasmol icon 3VEW A:1-112 X-RAY DIFFRACTION 2.352
rasmol icon 3VEX A:1-112 X-RAY DIFFRACTION 1.900
rasmol icon 3VEZ A:1-112 X-RAY DIFFRACTION 2.400
rasmol icon 3VF2 A:1-112 X-RAY DIFFRACTION 2.900
rasmol icon 3VF4 A:1-112 X-RAY DIFFRACTION 2.400
Representative CF domain (8004442)
Putative 6-carbamoyltransferase, TobZPutative carbamoyltransferase

Streptoalloteichus tenebrarius (1933)

 Q70IY1 129-333

rasmol icon 3VEN A:129-333 X-RAY DIFFRACTION 1.570
Clustered domains rasmol icon 3VEO A:129-333 X-RAY DIFFRACTION 2.1870
rasmol icon 3VER A:129-333 X-RAY DIFFRACTION 2.340
rasmol icon 3VES A:129-333 X-RAY DIFFRACTION 2.230
rasmol icon 3VET A:129-333 X-RAY DIFFRACTION 2.200
rasmol icon 3VEW A:129-333 X-RAY DIFFRACTION 2.352
rasmol icon 3VEX A:129-333 X-RAY DIFFRACTION 1.900
rasmol icon 3VEZ A:129-333 X-RAY DIFFRACTION 2.400
rasmol icon 3VF2 A:129-333 X-RAY DIFFRACTION 2.900
rasmol icon 3VF4 A:129-333 X-RAY DIFFRACTION 2.400
Representative CF domain (8004481)
Probable tRNA threonylcarbamoyladenosine biosynthesis protein KAE1 homolog

Pyrococcus abyssi (29292)

 Q9UXT7 1-106

rasmol icon 2IVN A:1-106 X-RAY DIFFRACTION 1.65
Clustered domains rasmol icon 2IVO A:1-106 X-RAY DIFFRACTION 2.90
rasmol icon 2IVO B:1-106 X-RAY DIFFRACTION 2.90
rasmol icon 2IVO C:1-106 X-RAY DIFFRACTION 2.90
rasmol icon 2IVO D:1-106 X-RAY DIFFRACTION 2.90
rasmol icon 2IVP A:1-106 X-RAY DIFFRACTION 2.50
Representative CF domain (8004482)
Probable tRNA threonylcarbamoyladenosine biosynthesis protein KAE1 homolog

Pyrococcus abyssi (29292)

 Q9UXT7 121-279

rasmol icon 2IVN A:121-279 X-RAY DIFFRACTION 1.65
Clustered domains rasmol icon 2IVO A:121-279 X-RAY DIFFRACTION 2.90
rasmol icon 2IVO B:121-279 X-RAY DIFFRACTION 2.90
rasmol icon 2IVO C:121-279 X-RAY DIFFRACTION 2.90
rasmol icon 2IVO D:121-279 X-RAY DIFFRACTION 2.90
rasmol icon 2IVP A:121-279 X-RAY DIFFRACTION 2.50
Representative CF domain (8017631)
Protein mlc
complexed with zn, mutant

Escherichia coli (562)

 P50456 82-194

Derived from SCOP domain 124558
rasmol icon 1Z6R A:82-194 X-RAY DIFFRACTION 2.70
Clustered domains rasmol icon 1Z6R B:82-194 X-RAY DIFFRACTION 2.70
rasmol icon 1Z6R C:82-194 X-RAY DIFFRACTION 2.70
rasmol icon 1Z6R D:82-194 X-RAY DIFFRACTION 2.70
rasmol icon 3BP8 A:82-194 X-RAY DIFFRACTION 2.85
rasmol icon 3BP8 B:82-194 X-RAY DIFFRACTION 2.85
Representative CF domain (8017632)
Protein mlc
complexed with zn, mutant

Escherichia coli (562)

 P50456 212-376

Derived from SCOP domain 124558
rasmol icon 1Z6R A:212-376 X-RAY DIFFRACTION 2.70
Clustered domains rasmol icon 1Z6R B:212-376 X-RAY DIFFRACTION 2.70
rasmol icon 1Z6R C:212-376 X-RAY DIFFRACTION 2.70
rasmol icon 1Z6R D:212-376 X-RAY DIFFRACTION 2.70
rasmol icon 3BP8 A:212-376 X-RAY DIFFRACTION 2.85
rasmol icon 3BP8 B:212-376 X-RAY DIFFRACTION 2.85
Representative CF domain (8017679)
Transcriptional regulator, ROK family
complexed with bme, gol, so4, zn

Vibrio cholerae O1 biovar El Tor str. N16961 (243277)

 Q9KQJ1 81-192

Derived from SCOP domain 124300
rasmol icon 1Z05 A:81-192 X-RAY DIFFRACTION 2.00
Representative CF domain (8017680)
Transcriptional regulator, ROK family
complexed with bme, gol, so4, zn

Vibrio cholerae O1 biovar El Tor str. N16961 (243277)

 Q9KQJ1 210-376

Derived from SCOP domain 124300
rasmol icon 1Z05 A:210-376 X-RAY DIFFRACTION 2.00
Representative CF domain (8018575)
DNA mismatch repair protein MutS

Thermus aquaticus (271)

 Q56215 132-234

Derived from SCOP domain 33740
rasmol icon 1EWQ A:132-234 X-RAY DIFFRACTION 2.20
Clustered domains rasmol icon 1EWQ B:1132-1234 X-RAY DIFFRACTION 2.20
rasmol icon 1EWR A:132-234 X-RAY DIFFRACTION 3.19
rasmol icon 1EWR B:1132-1234 X-RAY DIFFRACTION 3.19
rasmol icon 1FW6 A:132-234 X-RAY DIFFRACTION 2.70
rasmol icon 1FW6 B:1132-1234 X-RAY DIFFRACTION 2.70
rasmol icon 1NNE A:132-234 X-RAY DIFFRACTION 3.11
rasmol icon 1NNE B:1132-1234 X-RAY DIFFRACTION 3.11