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Fold

fold E2 binding domain-like (2000122)
beta-alpha-beta(2)-X-beta(2), 2 layers, a/b; antiparallel beta-sheet 15423
Circularly permuted variant of the ubiqutin-like topology; the C-terminal strand occupies the position of the N-terminal strand of the ubiquitin-like proteins but runs in the opposite direction

Protein Type

Globular proteinsFold into compact units. Soluble in aqueous solutions

Children

  • superfamily E2 binding domain-like (3000147)
    structural domain, shared by the activating enzymes of the ubiquitin-lke proteins of different domain architectures
Domains PDB ID RegionMethodResolution
Representative CF domain (8003528)
strand flipChange of the orientation of the strand with respect to the core elements.
NEDD8-activating enzyme E1 catalytic subunit
complexed with zn, mutant

Homo sapiens (9606)

 Q8TBC4 370-463

Derived from SCOP domain 123786
rasmol icon 3DBH B:349-442 X-RAY DIFFRACTION 2.85
Clustered domains rasmol icon 1R4M B:349-917 The ends of this domain were trimmed X-RAY DIFFRACTION 3.0
rasmol icon 1R4M D:349-917 The ends of this domain were trimmed X-RAY DIFFRACTION 3.0
rasmol icon 1R4M F:349-917 The ends of this domain were trimmed X-RAY DIFFRACTION 3.0
rasmol icon 1R4M H:349-917 The ends of this domain were trimmed X-RAY DIFFRACTION 3.0
rasmol icon 1R4N B:349-917 The ends of this domain were trimmed X-RAY DIFFRACTION 3.6
rasmol icon 1R4N D:349-917 The ends of this domain were trimmed X-RAY DIFFRACTION 3.6
rasmol icon 1R4N F:349-917 The ends of this domain were trimmed X-RAY DIFFRACTION 3.6
rasmol icon 1R4N H:349-917 The ends of this domain were trimmed X-RAY DIFFRACTION 3.6
rasmol icon 1TT5 B:349-1008 The ends of this domain were trimmed X-RAY DIFFRACTION 2.6
rasmol icon 1TT5 D:349-1008 Some residues were not observed X-RAY DIFFRACTION 2.6
rasmol icon 1Y8X B:349-440 The ends of this domain were trimmed X-RAY DIFFRACTION 2.4
rasmol icon 1YOV B:349-437 Some residues were not observed X-RAY DIFFRACTION 2.6
rasmol icon 1YOV D:349-436 The ends of this domain were trimmed X-RAY DIFFRACTION 2.6
rasmol icon 2LQ7 A:349-442 SOLUTION NMR n/a
rasmol icon 2NVU B:2349-2442 X-RAY DIFFRACTION 2.80
rasmol icon 3DBH D:349-442 X-RAY DIFFRACTION 2.85
rasmol icon 3DBH F:349-441 The ends of this domain were trimmed X-RAY DIFFRACTION 2.85
rasmol icon 3DBH H:349-441 The ends of this domain were trimmed X-RAY DIFFRACTION 2.85
rasmol icon 3DBL B:349-442 X-RAY DIFFRACTION 2.90
rasmol icon 3DBL D:349-442 X-RAY DIFFRACTION 2.90
rasmol icon 3DBL F:349-441 The ends of this domain were trimmed X-RAY DIFFRACTION 2.90
rasmol icon 3DBL H:349-441 The ends of this domain were trimmed X-RAY DIFFRACTION 2.90
rasmol icon 3DBR B:349-442 X-RAY DIFFRACTION 3.05
rasmol icon 3DBR D:349-441 The ends of this domain were trimmed X-RAY DIFFRACTION 3.05
rasmol icon 3DBR F:349-441 The ends of this domain were trimmed X-RAY DIFFRACTION 3.05
rasmol icon 3DBR H:349-441 The ends of this domain were trimmed X-RAY DIFFRACTION 3.05
rasmol icon 3FN1 A:350-441 The ends of this domain were trimmed X-RAY DIFFRACTION 2.50
rasmol icon 3GZN B:370-462 The ends of this domain were trimmed X-RAY DIFFRACTION 3.00
rasmol icon 3GZN D:370-462 The ends of this domain were trimmed X-RAY DIFFRACTION 3.00
Representative CF domain (8003529)
strand flipChange of the orientation of the strand with respect to the core elements.
Ubiquitin-activating enzyme E1 1
complexed with pro and ubiquitin

Saccharomyces cerevisiae (4932)

 P22515 929-1024

rasmol icon 3CMM C:929-1024 X-RAY DIFFRACTION 2.70
Clustered domains rasmol icon 3CMM A:929-1024 X-RAY DIFFRACTION 2.70

Saccharomyces cerevisiae S288c (559292)

rasmol icon 4NNJ A:929-1024 X-RAY DIFFRACTION 2.400

Saccharomyces cerevisiae S288c (559292)

rasmol icon 4NNJ C:929-1024 X-RAY DIFFRACTION 2.400
Representative CF domain (8003530)
strand flipChange of the orientation of the strand with respect to the core elements.
SUMO-activating enzyme subunit 2
complexed with atp, mg, zn

Homo sapiens (9606)

 Q9UBT2 447-550

rasmol icon 1Y8Q D:447-550 X-RAY DIFFRACTION 2.25
Clustered domains rasmol icon 1Y8Q B:447-550 X-RAY DIFFRACTION 2.25
rasmol icon 1Y8R B:447-550 X-RAY DIFFRACTION 2.75
rasmol icon 1Y8R E:447-550 X-RAY DIFFRACTION 2.75
rasmol icon 3KYC B:447-550 X-RAY DIFFRACTION 2.450
rasmol icon 3KYD B:447-548 The ends of this domain were trimmed X-RAY DIFFRACTION 2.610
rasmol icon 4W5V B:447-549 The ends of this domain were trimmed X-RAY DIFFRACTION 2.500
rasmol icon 5FQ2 B:447-547 The ends of this domain were trimmed X-RAY DIFFRACTION 2.201