Parents

  • fold Ferredoxin-like (2000014)
    beta-alpha-beta(2)-alpha-beta; 2 layers, a/b; antiparallel beta-sheet, order: 4132
    Derived from SCOP 54861
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Superfamily

superfamily ACT-like (3000006)
regulatory domain linked to a wide range of metabolic enzymes
Derived from SCOP 55021

Children

  • family Phosphoglycerate dehydrogenase, regulatory (C-terminal) domain (4000051)
    Derived from SCOP 55022
  • family Glycine cleavage system transcriptional repressor (4000142)
    tandem repeat of two ACT-like domains, swapped domain dimer
    Derived from SCOP 110980
  • family TM1266-like (4000163)
    PfamB 015436, stand-alone tetrameric protein, there are single beta-sheet dimers, whose beta-sheets are packed in parallel fasion in the tetramer
    Derived from SCOP 160329
  • family IlvH-like (4000264)
    Duplication: tandem repeat of two ACT-like domains, dimer, the N- and C-terminal domains have different dimerisation modes
    Derived from SCOP 143376
  • family SP0238-like (4000268)
    stand-alone protein, dimer, the dimerization interface is formed by parallel packing of the subunit beta-sheets
    Derived from SCOP 143381
  • family Atu0741-like (4000270)
    duplication: tandem repeat of two ACT-like domains, contains strand invasion of extra N-terminal strand into the C-terminal domain beta-sheet, dimerizes with the formation of orthogonally packed intersubunit beta-sheets
    Derived from SCOP 143384
  • family VC0802-like (4000273)
    duplication: tandem repeat of two ACT-like domains, contains circular permutation (the C-terminal strand replacement with extra N-terminal strand), dimerizes with the formation of orthogonally packed intersubunit beta-sheets
    Derived from SCOP 143387
  • family BT0572-like (4000275)
    duplication: tandem repeat of two ACT-like domains, dimerizes with the formation of orthogonally packed intersubunit beta-sheets
    Derived from SCOP 143395
  • family NIL domain-like (4001937)
    Pfam 09383
    Derived from SCOP 160322
Domains PDB ID RegionMethodResolution
Representative SF domain (8001021)
D-3-phosphoglycerate dehydrogenase (EC 11.1.95) (PGDH).
complexed with nad, mutant

Escherichia coli (562)

 P0A9T0 327-409

Derived from SCOP domain 118934
rasmol icon 1SC6 A:327-409 X-RAY DIFFRACTION 2.09
Clustered domains

Escherichia coli K-12 (83333)

rasmol icon 1PSD A:327-409 X-RAY DIFFRACTION 2.75

Escherichia coli K-12 (83333)

rasmol icon 1PSD B:327-409 X-RAY DIFFRACTION 2.75
rasmol icon 1SC6 B:327-409 X-RAY DIFFRACTION 2.09
rasmol icon 1SC6 C:327-409 X-RAY DIFFRACTION 2.09
rasmol icon 1SC6 D:327-409 X-RAY DIFFRACTION 2.09
rasmol icon 1YBA A:327-409 X-RAY DIFFRACTION 2.24
rasmol icon 1YBA B:327-409 X-RAY DIFFRACTION 2.24
rasmol icon 1YBA C:327-409 X-RAY DIFFRACTION 2.24
rasmol icon 1YBA D:327-409 X-RAY DIFFRACTION 2.24
rasmol icon 2P9C A:327-409 X-RAY DIFFRACTION 2.46
rasmol icon 2P9C B:327-409 X-RAY DIFFRACTION 2.46
rasmol icon 2P9E A:327-409 X-RAY DIFFRACTION 2.60
rasmol icon 2P9E B:327-409 X-RAY DIFFRACTION 2.60
rasmol icon 2P9E C:327-409 X-RAY DIFFRACTION 2.60
rasmol icon 2P9E D:327-409 X-RAY DIFFRACTION 2.60
rasmol icon 2P9G A:327-409 X-RAY DIFFRACTION 2.80
rasmol icon 2P9G B:327-409 X-RAY DIFFRACTION 2.80
rasmol icon 2PA3 A:327-409 X-RAY DIFFRACTION 2.74
Representative SF domain (8003859)
Glycine cleavage system transcriptional repressor, putative

Vibrio cholerae (666)

 Q9KQ45 2-81

Derived from SCOP domain 107737
rasmol icon 1U8S A:4-83 X-RAY DIFFRACTION 2.45
Clustered domains rasmol icon 1U8S B:4-83 X-RAY DIFFRACTION 2.45
Representative SF domain (8003860)
Glycine cleavage system transcriptional repressor, putative

Vibrio cholerae (666)

 Q9KQ45 88-178

Derived from SCOP domain 107738
rasmol icon 1U8S A:90-180 X-RAY DIFFRACTION 2.45
Clustered domains rasmol icon 1U8S B:90-180 X-RAY DIFFRACTION 2.45
Representative SF domain (8003866)
Putative uncharacterized protein
complexed with acy, gol, po4

Thermotoga maritima MSB8 (243274)

 Q9X0Z3 2-81

Derived from SCOP domain 148528
rasmol icon 2NZC A:2-81 X-RAY DIFFRACTION 1.95
Clustered domains rasmol icon 2NZC B:2-81 X-RAY DIFFRACTION 1.95
rasmol icon 2NZC C:2-81 X-RAY DIFFRACTION 1.95
rasmol icon 2NZC D:2-81 X-RAY DIFFRACTION 1.95
Representative SF domain (8003871)
Acetolactate synthase isozyme 3 small subunit
complexed with 1pe, mg, p33

Escherichia coli (562)

 P00894 2-76

Derived from SCOP domain 132760
rasmol icon 2F1F A:2-76 X-RAY DIFFRACTION 1.750
Clustered domains rasmol icon 2F1F B:2-76 X-RAY DIFFRACTION 1.750
Representative SF domain (8003872)
Acetolactate synthase isozyme 3 small subunit
complexed with 1pe, mg, p33

Escherichia coli (562)

 P00894 80-163

Derived from SCOP domain 132761
rasmol icon 2F1F A:80-163 X-RAY DIFFRACTION 1.750
Clustered domains rasmol icon 2F1F B:80-158 The ends of this domain were trimmed X-RAY DIFFRACTION 1.750
Representative SF domain (8003880)
UPF0237 protein SP_0238
complexed with k

Streptococcus pneumoniae TIGR4 (170187)

 P67382 1-79

Derived from SCOP domain 125475
rasmol icon 1ZPV A:1-79 X-RAY DIFFRACTION 1.90
Clustered domains rasmol icon 1ZPV B:1-79 X-RAY DIFFRACTION 1.90
rasmol icon 1ZPV C:1-79 X-RAY DIFFRACTION 1.90
Representative SF domain (8003885)
Acetohydroxyacid synthase small subunit Related
complexed with his

Bacteroides thetaiotaomicron VPI-5482 (226186)

 Q8AA93 71-133

Derived from SCOP domain 132652
rasmol icon 2F06 A:71-133 X-RAY DIFFRACTION 2.10
Clustered domains rasmol icon 2F06 B:71-133 X-RAY DIFFRACTION 2.10
Representative SF domain (8003886)
Acetohydroxyacid synthase small subunit Related
complexed with his

Bacteroides thetaiotaomicron VPI-5482 (226186)

 Q8AA93 1-70

Derived from SCOP domain 132653
rasmol icon 2F06 A:1-70 X-RAY DIFFRACTION 2.10
Clustered domains rasmol icon 2F06 B:1-70 X-RAY DIFFRACTION 2.10
Representative SF domain (8003892)
Putative uncharacterized protein

Vibrio cholerae (666)

 Q9KTT6 23-70

Derived from SCOP domain 125720
rasmol icon 1ZVP D:23-70 X-RAY DIFFRACTION 2.20
Clustered domains rasmol icon 1ZVP A:23-70 X-RAY DIFFRACTION 2.20
rasmol icon 1ZVP B:23-70 X-RAY DIFFRACTION 2.20
rasmol icon 1ZVP C:23-70 X-RAY DIFFRACTION 2.20
Representative SF domain (8003899)
Putative uncharacterized protein Atu0741

Agrobacterium fabrum str. C58 (176299)

 A9CJY8 13-62

Derived from SCOP domain 125109
rasmol icon 1ZHV A:13-62 X-RAY DIFFRACTION 1.50
Representative SF domain (8017540)
D-3-phosphoglycerate dehydrogenase (EC 11.1.95) (PGDH).
complexed with tar

Mycobacterium tuberculosis (1773)

 P0A544 453-527

Derived from SCOP domain 123152
rasmol icon 1YGY A:454-528 X-RAY DIFFRACTION 2.30
Representative SF domain (8018383)
Methionine import ATP-binding protein MetN

Escherichia coli K-12 (83333)

 P30750 265-343

Derived from SCOP domain 157730
rasmol icon 3DHW C:265-343 X-RAY DIFFRACTION 3.70
Clustered domains rasmol icon 3DHW D:265-343 X-RAY DIFFRACTION 3.70
rasmol icon 3DHW G:265-343 X-RAY DIFFRACTION 3.70
rasmol icon 3DHW H:265-343 X-RAY DIFFRACTION 3.70
rasmol icon 3DHX A:20-98 X-RAY DIFFRACTION 2.10
rasmol icon 3DHX B:20-98 X-RAY DIFFRACTION 2.10
rasmol icon 3TUI C:265-343 X-RAY DIFFRACTION 2.900
rasmol icon 3TUI D:265-343 X-RAY DIFFRACTION 2.900
rasmol icon 3TUI G:265-343 X-RAY DIFFRACTION 2.900
rasmol icon 3TUI H:265-343 X-RAY DIFFRACTION 2.900
rasmol icon 3TUJ C:265-343 X-RAY DIFFRACTION 4.0000
rasmol icon 3TUJ D:265-343 X-RAY DIFFRACTION 4.0000
rasmol icon 3TUZ C:265-343 X-RAY DIFFRACTION 3.4000
rasmol icon 3TUZ D:265-343 X-RAY DIFFRACTION 3.4000
rasmol icon 3TUZ G:265-343 X-RAY DIFFRACTION 3.4000
rasmol icon 3TUZ H:265-339 The ends of this domain were trimmed X-RAY DIFFRACTION 3.4000