Parents

  • fold MoeB-like (2000082)
    3 layers: a/b/a, mixed beta-sheet of 8 strands, order 32145678, strands 6 and 8 are antiparallel to the rest
    Derived from SCOP 69571
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Superfamily

superfamily Activating enzymes of the ubiquitin-like proteins (3000112)
transfer adenylyl group to the C-terminal carboxyl group of the ubiquitin and MoaD/ThiS-related proteins the ATP nucleotide-binding site is similar to that of the NAD-binding Rossmann-folds
Derived from SCOP 69572

Children

Domains PDB ID RegionMethodResolution
Representative SF domain (8003535)
SUMO-activating enzyme subunit 1
complexed with atp, mg, zn

Homo sapiens (9606)

 Q9UBE0 10-222,297-345

rasmol icon 1Y8Q A:10-222,297-345 X-RAY DIFFRACTION 2.25
Clustered domains rasmol icon 1Y8Q C:10-222,297-345 X-RAY DIFFRACTION 2.25
rasmol icon 1Y8R A:10-222,297-345 X-RAY DIFFRACTION 2.75
rasmol icon 1Y8R D:10-222,297-345 X-RAY DIFFRACTION 2.75
rasmol icon 3KYC A:10-222,297-345 X-RAY DIFFRACTION 2.450
rasmol icon 3KYD A:25-222,297-345 The ends of this domain were trimmed X-RAY DIFFRACTION 2.610
Representative SF domain (8003536)
Sulfur carrier protein moaD adenylyltransferase
complexed with so4, zn

Escherichia coli (562)

 P12282 2-248

Derived from SCOP domain 67377
rasmol icon 1JW9 B:2-248 X-RAY DIFFRACTION 1.7
Clustered domains rasmol icon 1JWA B:2-240 The ends of this domain were trimmed X-RAY DIFFRACTION 2.9
rasmol icon 1JWB B:2-248 X-RAY DIFFRACTION 2.1
Representative SF domain (8003537)
NEDD8-activating enzyme E1 regulatory subunit
complexed with zn, mutant

Homo sapiens (9606)

 Q13564 6-168,488-534

Derived from SCOP domain 157468
rasmol icon 3DBH A:6-168,488-534 X-RAY DIFFRACTION 2.85
Clustered domains rasmol icon 1R4M A:6-168,488-534 X-RAY DIFFRACTION 3.0
rasmol icon 1R4M C:6-168,488-534 X-RAY DIFFRACTION 3.0
rasmol icon 1R4M E:6-168,488-534 X-RAY DIFFRACTION 3.0
rasmol icon 1R4M G:6-168,488-534 X-RAY DIFFRACTION 3.0
rasmol icon 1R4N A:6-168,488-534 X-RAY DIFFRACTION 3.6
rasmol icon 1R4N C:6-168,488-534 X-RAY DIFFRACTION 3.6
rasmol icon 1R4N E:6-168,488-534 X-RAY DIFFRACTION 3.6
rasmol icon 1R4N G:6-168,488-534 X-RAY DIFFRACTION 3.6
rasmol icon 1TT5 A:6-168,488-534 X-RAY DIFFRACTION 2.6
rasmol icon 1TT5 C:7-168,488-534 The ends of this domain were trimmed X-RAY DIFFRACTION 2.6
rasmol icon 1YOV A:6-168,488-534 X-RAY DIFFRACTION 2.6
rasmol icon 1YOV C:9-168,488-534 The ends of this domain were trimmed X-RAY DIFFRACTION 2.6
rasmol icon 2NVU A:6-168,488-534 X-RAY DIFFRACTION 2.80
rasmol icon 3DBH C:6-168,488-534 X-RAY DIFFRACTION 2.85
rasmol icon 3DBH E:6-168,488-534 X-RAY DIFFRACTION 2.85
rasmol icon 3DBH G:6-168,488-534 X-RAY DIFFRACTION 2.85
rasmol icon 3DBL A:6-168,488-534 X-RAY DIFFRACTION 2.90
rasmol icon 3DBL C:6-168,488-534 X-RAY DIFFRACTION 2.90
rasmol icon 3DBL E:6-168,488-534 X-RAY DIFFRACTION 2.90
rasmol icon 3DBL G:6-168,488-534 X-RAY DIFFRACTION 2.90
rasmol icon 3DBR A:6-168,488-534 X-RAY DIFFRACTION 3.05
rasmol icon 3DBR C:6-168,488-534 X-RAY DIFFRACTION 3.05
rasmol icon 3DBR E:6-168,488-534 X-RAY DIFFRACTION 3.05
rasmol icon 3DBR G:6-168,488-534 X-RAY DIFFRACTION 3.05
rasmol icon 3GZN A:15-175,495-541 The ends of this domain were trimmed X-RAY DIFFRACTION 3.00
rasmol icon 3GZN C:14-175,495-541 The ends of this domain were trimmed X-RAY DIFFRACTION 3.00
Representative SF domain (8003540)
Ubiquitin-activating enzyme E1 1
complexed with pro and ubiquitin

Saccharomyces cerevisiae (4932)

 P22515 415-589,862-916

rasmol icon 3CMM C:415-589,862-916 X-RAY DIFFRACTION 2.70
Clustered domains rasmol icon 3CMM A:415-589,862-916 X-RAY DIFFRACTION 2.70

Saccharomyces cerevisiae S288c (559292)

rasmol icon 4NNJ A:415-589,862-916 X-RAY DIFFRACTION 2.400

Saccharomyces cerevisiae S288c (559292)

rasmol icon 4NNJ C:415-589,862-916 X-RAY DIFFRACTION 2.400
Representative SF domain (8003541)
SUMO-activating enzyme subunit 2
complexed with atp, mg, zn

Homo sapiens (9606)

 Q9UBT2 6-161,383-446

rasmol icon 1Y8Q D:6-161,383-446 X-RAY DIFFRACTION 2.25
Clustered domains rasmol icon 1Y8Q B:6-161,383-446 X-RAY DIFFRACTION 2.25
rasmol icon 1Y8R B:6-161,383-446 X-RAY DIFFRACTION 2.75
rasmol icon 1Y8R E:6-161,383-446 X-RAY DIFFRACTION 2.75
rasmol icon 3KYC B:6-161,383-446 X-RAY DIFFRACTION 2.450
rasmol icon 3KYD B:6-161,383-446 X-RAY DIFFRACTION 2.610
Representative SF domain (8003542)
NEDD8-activating enzyme E1 catalytic subunit
complexed with zn, mutant

Homo sapiens (9606)

 Q8TBC4 60-225,309-369

Derived from SCOP domain 123786
rasmol icon 3DBH B:39-204,288-348 X-RAY DIFFRACTION 2.85
Clustered domains rasmol icon 1R4M B:39-204,288-348 X-RAY DIFFRACTION 3.0
rasmol icon 1R4M D:39-204,288-348 X-RAY DIFFRACTION 3.0
rasmol icon 1R4M F:39-204,288-348 X-RAY DIFFRACTION 3.0
rasmol icon 1R4M H:39-204,288-348 X-RAY DIFFRACTION 3.0
rasmol icon 1R4N B:39-204,288-348 X-RAY DIFFRACTION 3.6
rasmol icon 1R4N D:39-204,288-348 X-RAY DIFFRACTION 3.6
rasmol icon 1R4N F:39-204,288-348 X-RAY DIFFRACTION 3.6
rasmol icon 1R4N H:39-204,288-348 X-RAY DIFFRACTION 3.6
rasmol icon 1TT5 B:39-204,288-348 X-RAY DIFFRACTION 2.6
rasmol icon 1TT5 D:39-204,288-348 X-RAY DIFFRACTION 2.6
rasmol icon 1YOV B:39-204,288-348 X-RAY DIFFRACTION 2.6
rasmol icon 1YOV D:39-204,288-348 X-RAY DIFFRACTION 2.6
rasmol icon 2NVU B:2039-2204,2288-2348 X-RAY DIFFRACTION 2.80
rasmol icon 3DBH D:39-204,288-348 X-RAY DIFFRACTION 2.85
rasmol icon 3DBH F:39-204,288-348 X-RAY DIFFRACTION 2.85
rasmol icon 3DBH H:39-204,288-348 X-RAY DIFFRACTION 2.85
rasmol icon 3DBL B:39-204,288-348 X-RAY DIFFRACTION 2.90
rasmol icon 3DBL D:39-204,288-348 X-RAY DIFFRACTION 2.90
rasmol icon 3DBL F:39-204,288-348 X-RAY DIFFRACTION 2.90
rasmol icon 3DBL H:39-204,288-348 X-RAY DIFFRACTION 2.90
rasmol icon 3DBR B:39-204,288-348 X-RAY DIFFRACTION 3.05
rasmol icon 3DBR D:39-204,288-348 X-RAY DIFFRACTION 3.05
rasmol icon 3DBR F:39-204,288-348 X-RAY DIFFRACTION 3.05
rasmol icon 3DBR H:39-204,288-348 X-RAY DIFFRACTION 3.05
rasmol icon 3GZN B:60-225,309-369 X-RAY DIFFRACTION 3.00
rasmol icon 3GZN D:60-225,309-369 X-RAY DIFFRACTION 3.00
Representative SF domain (8017546)
Ubiquitin-activating enzyme E1 1
complexed with pro and ubiquitin

Saccharomyces cerevisiae (4932)

 P22515 11-177,358-394

rasmol icon 3CMM C:11-177,358-394 X-RAY DIFFRACTION 2.70
Clustered domains rasmol icon 3CMM A:12-177,358-394 The ends of this domain were trimmed X-RAY DIFFRACTION 2.70

Saccharomyces cerevisiae S288c (559292)

rasmol icon 4NNJ A:11-177,358-394 X-RAY DIFFRACTION 2.400

Saccharomyces cerevisiae S288c (559292)

rasmol icon 4NNJ C:11-177,358-394 X-RAY DIFFRACTION 2.400