Hypothetical Evolutionary Event

Duplication-fusion event in the histone domain of SOS (14)

Duplication-fusion event in the histone domain of SOS. The histone domain contains two tandem histone fold repeats arranged as in the histone dimer. This event is similar to the event that have occurred in bacterial histone-fold proteins.

Nodes

  • family Histone domain of Son of Sevenless (Sos-1) (4004029)
    contains two tandem histone folds arranged as the subunits of histone H2A-H2B dimer. The first half is structurally similar to histone H2B whereas the second half has sequence and structural similarity to histone H2A.