Hypothetical Evolutionary Event

Duplication-fusion-deletion in the Hydroxyisobutyrate dehydrogenase/6-phosphogluconate dehydrogenase-like family (2)

Event converts a hydroxyisobutyrate dehydrogenase-like dimer into a single-chain 6-phosphogluconate dehydrogenase-like monomer with the redundant NAD-binding domain deleted; the dimeric biological unit of latter retains similarity to the tetrameric unit of the former

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