Interrelationship

repeated domain D-2-hydroxyacid dehydrohenase-like half-domain (7000002)

topological repeat in the D-2-hydroxyacid dehydrohenase-like superfamily fold

Nodes

  • superfamily D-2-hydroxyacid dehydrogenase-like (3000044)
    2 Rossmann-like domains, swapped with the C-terminal helices; the numbers of strands in each domain vary between the families; the NAD-binding site is in the C-terminal domain
    Derived from SCOP 51735
Domains PDB ID RegionMethodResolution
Representative IR domain (8000988)
Alanine dehydrogenase (EC 14.1.1).
complexed with pyr

Phormidium lapideum (32060)

 O52942 164-327

Derived from SCOP domain 30102
rasmol icon 1SAY A:164-327 X-RAY DIFFRACTION 2.1
Clustered domains rasmol icon 1PJB A:164-327 X-RAY DIFFRACTION 2.1
rasmol icon 1PJC A:164-327 X-RAY DIFFRACTION 2.00
Representative IR domain (8000989)
Alanine dehydrogenase (EC 14.1.1).
complexed with pyr

Phormidium lapideum (32060)

 O52942 1-163

Derived from SCOP domain 31362
rasmol icon 1SAY A:1-163 X-RAY DIFFRACTION 2.1
Clustered domains rasmol icon 1PJB A:1-163 X-RAY DIFFRACTION 2.1
rasmol icon 1PJC A:1-163 X-RAY DIFFRACTION 2.00
Representative IR domain (8000997)
Adenosylhomocysteinase (EC 33.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase)
complexed with ipa, nah, noc

Homo sapiens (9606)

 P23526 213-376

Derived from SCOP domain 84616
rasmol icon 1LI4 A:213-376 X-RAY DIFFRACTION 2.01
Clustered domains rasmol icon 1A7A A:213-376 X-RAY DIFFRACTION 2.8
rasmol icon 1A7A B:213-376 X-RAY DIFFRACTION 2.8
rasmol icon 3NJ4 A:213-376 X-RAY DIFFRACTION 2.50
rasmol icon 3NJ4 B:213-376 X-RAY DIFFRACTION 2.50
rasmol icon 3NJ4 C:213-376 X-RAY DIFFRACTION 2.50
rasmol icon 3NJ4 D:213-376 X-RAY DIFFRACTION 2.50
rasmol icon 4PFJ A:213-376 X-RAY DIFFRACTION 2.301
rasmol icon 4PFJ B:213-376 X-RAY DIFFRACTION 2.301
rasmol icon 4PGF A:213-376 X-RAY DIFFRACTION 2.592
rasmol icon 4PGF B:213-376 X-RAY DIFFRACTION 2.592
rasmol icon 4YVF A:213-376 X-RAY DIFFRACTION 2.70
rasmol icon 4YVF B:213-376 X-RAY DIFFRACTION 2.70
Representative IR domain (8000998)
Adenosylhomocysteinase (EC 33.1.1) (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase)
complexed with ipa, nah, noc

Homo sapiens (9606)

 P23526 46-208

Derived from SCOP domain 84617
rasmol icon 1LI4 A:46-208 X-RAY DIFFRACTION 2.01
Clustered domains rasmol icon 1A7A A:46-208 X-RAY DIFFRACTION 2.8
rasmol icon 1A7A B:46-208 X-RAY DIFFRACTION 2.8
rasmol icon 3NJ4 A:46-208 X-RAY DIFFRACTION 2.50
rasmol icon 3NJ4 B:46-208 X-RAY DIFFRACTION 2.50
rasmol icon 3NJ4 C:46-208 X-RAY DIFFRACTION 2.50
rasmol icon 3NJ4 D:46-208 X-RAY DIFFRACTION 2.50
rasmol icon 4PFJ A:46-208 X-RAY DIFFRACTION 2.301
rasmol icon 4PFJ B:46-208 X-RAY DIFFRACTION 2.301
rasmol icon 4PGF A:46-208 X-RAY DIFFRACTION 2.592
rasmol icon 4PGF B:46-208 X-RAY DIFFRACTION 2.592
rasmol icon 4YVF A:46-208 X-RAY DIFFRACTION 2.70
rasmol icon 4YVF B:46-208 X-RAY DIFFRACTION 2.70
Representative IR domain (8001004)
Formate dehydrogenase (EC 12.1.2) (NAD-dependent formate dehydrogenase) (FDH)

Pseudomonas sp. 101 (33067)

 P33160 189-359

Derived from SCOP domain 30088
rasmol icon 2NAC A:188-358 X-RAY DIFFRACTION 1.80
Clustered domains rasmol icon 2GO1 A:188-358 X-RAY DIFFRACTION 2.10
rasmol icon 2GUG A:188-358 X-RAY DIFFRACTION 2.28
rasmol icon 2GUG B:188-358 X-RAY DIFFRACTION 2.28
rasmol icon 2GUG C:188-358 X-RAY DIFFRACTION 2.28
rasmol icon 2GUG D:188-358 X-RAY DIFFRACTION 2.28
rasmol icon 2NAC B:188-358 X-RAY DIFFRACTION 1.80
rasmol icon 2NAD A:188-358 X-RAY DIFFRACTION 2.05
rasmol icon 2NAD B:188-358 X-RAY DIFFRACTION 2.05
Representative IR domain (8001005)
Formate dehydrogenase (EC 12.1.2) (NAD-dependent formate dehydrogenase) (FDH)

Pseudomonas sp. 101 (33067)

 P33160 2-165

Derived from SCOP domain 31348
rasmol icon 2NAC A:1-164 X-RAY DIFFRACTION 1.80
Clustered domains rasmol icon 2GO1 A:1-164 X-RAY DIFFRACTION 2.10
rasmol icon 2GUG A:1-164 X-RAY DIFFRACTION 2.28
rasmol icon 2GUG B:1-164 X-RAY DIFFRACTION 2.28
rasmol icon 2GUG C:1-164 X-RAY DIFFRACTION 2.28
rasmol icon 2GUG D:1-164 X-RAY DIFFRACTION 2.28
rasmol icon 2NAC B:1-164 X-RAY DIFFRACTION 1.80
rasmol icon 2NAD A:1-164 X-RAY DIFFRACTION 2.05
rasmol icon 2NAD B:1-164 X-RAY DIFFRACTION 2.05