Interrelationship

biounitgen KARI I dimerisation/ KARI II duplicated region (7000004)

homologous to the C-terminal region of the KARI I; probably resulted from duplication/deletion event in a KARI I-like ancestor

Nodes

  • family Ketol-acid reductoisomerase (KARI)-like (4000106)
    extra C-terminal helices form dimerisation subdomain, where the different subunits interlock; in some proteins this region is duplicated and the repeated regions are similarly packed as in the dimer, forming a figure-8 knot
    Derived from SCOP 51868
Domains PDB ID RegionMethodResolution
Representative IR domain (8001127)
Ketol-acid reductoisomerase (EC 11.1.86) (Acetohydroxy-acid isomeroreductase) (Alpha-keto-beta-hydroxylacil reductoisomerase)

Pseudomonas aeruginosa (287)

 Q9HVA2 183-327

Derived from SCOP domain 85946
rasmol icon 1NP3 A:183-327 X-RAY DIFFRACTION 2.00
Clustered domains rasmol icon 1NP3 B:183-327 X-RAY DIFFRACTION 2.00
rasmol icon 1NP3 C:183-327 X-RAY DIFFRACTION 2.00
rasmol icon 1NP3 D:183-327 X-RAY DIFFRACTION 2.00
Representative IR domain (8001131)
Ketol-acid reductoisomerase, chloroplast precursor (EC 11.1.86) (Acetohydroxy-acid reductoisomerase) (Alpha-keto-beta-hydroxylacil reductoisomerase)

Spinacia oleracea (3562)

 Q01292 308-455

Derived from SCOP domain 18785
rasmol icon 1QMG A:308-455 X-RAY DIFFRACTION 1.6
Clustered domains rasmol icon 1QMG B:308-455 X-RAY DIFFRACTION 1.6
rasmol icon 1QMG C:308-455 X-RAY DIFFRACTION 1.6
rasmol icon 1QMG D:308-455 X-RAY DIFFRACTION 1.6
rasmol icon 1YVE I:308-455 X-RAY DIFFRACTION 1.65
rasmol icon 1YVE J:308-455 X-RAY DIFFRACTION 1.65
rasmol icon 1YVE K:308-455 X-RAY DIFFRACTION 1.65
rasmol icon 1YVE L:308-455 X-RAY DIFFRACTION 1.65
Representative IR domain (8001132)
Ketol-acid reductoisomerase, chloroplast precursor (EC 11.1.86) (Acetohydroxy-acid reductoisomerase) (Alpha-keto-beta-hydroxylacil reductoisomerase)

Spinacia oleracea (3562)

 Q01292 456-595

Derived from SCOP domain 18785
rasmol icon 1QMG A:456-595 X-RAY DIFFRACTION 1.6
Clustered domains rasmol icon 1QMG B:456-595 X-RAY DIFFRACTION 1.6
rasmol icon 1QMG C:456-595 X-RAY DIFFRACTION 1.6
rasmol icon 1QMG D:456-595 X-RAY DIFFRACTION 1.6
rasmol icon 1YVE I:456-595 X-RAY DIFFRACTION 1.65
rasmol icon 1YVE J:456-595 X-RAY DIFFRACTION 1.65
rasmol icon 1YVE K:456-595 X-RAY DIFFRACTION 1.65
rasmol icon 1YVE L:456-595 X-RAY DIFFRACTION 1.65